Hi . Welcome to the community! If amitriptyline is effective for you, you should be able to come off zopliclone, but your body might need some time to adjust. We are not medical experts, however, so it's best to talk to your doctor. Your pharmacist might also be a good source of information for determining whether there might be side effects when you come off zopliclone. Do you know what triggered your insomnia? Have you had symptoms for long? Thinking of you and wishing you the best. - Lori (Team Member)